Thursday, June 6
viruses, vlps & nanoparticles
8:30 AM – 9:00 AM Registration (at the registration desk in Portus Congress Center)
Session Chairs: Ivana Petrović Koshmak (Sartorius BIA Separations) and Maja Leskovec (Sartorius BIA Separations, Slovenia)
9:00 AM – 9:35 AM Where does the cell and gene field need to go to thrive? Critical considerations as you move your programs forward (Andrew Knudten, Advanced Medicine Partners)
9:35 AM – 10:00 AM Key parameters to improve your AAV production (Marine Guise, Polyplus) – Online
10:00 AM – 10:25 AM New approaches for viral vector genome integrity evaluation (David Dobnik, National Institue of Biology)
10:25 AM – 10:55 AM Coffee Break
Session Chairs: Bernd Giebel (Essen University Hospital, Germany) and Andrew Knudten ( Advanced Medicine Partners, USA)
10:55 AM – 11:20 AM Development of capture and polishing chromatography steps using Sartorius CIM monolithic chromatography technology for a novel AAV serotype (Christopher Nieder, CBM) – Online
11:20 AM – 11:45 AM You don’t need affinity to purify rAAV part 2 & beyond empty | full separation (Michael J. Hatfield, Advanced Medicine Partners)
11:45 AM – 12:10 PM Advancing AAV empty/full capsids separation with ExoReady™ platform: harnessing the power of monolithic columns (Tiago Albano, Exhotera) – Online
12:10 PM – 1:10 PM Lunch in the Congress Center (provided by the organizer)
Session Chairs: Manfred Reiter (Nuvonis, Austria) and Sebastijan Peljhan (Sartorius BIA Separations, Slovenia)
1:10 PM – 1:45 PM GET+VVIRAL: a purification toolbox for the gene-editing tools and viral vectors (Stefano Menegatti, North Carolina State University) – Online
1:45 PM – 2:10 PM Two streams, a single process: optimizing AAV production for improved purification performance (Ivana Petrović Koshmak, Sartorius BIA Separations)
2:10 PM – 2:35 PM Limitations of various analytical techniques in characterizing recombinant adeno-associated virus empty capsids (Kazuhiro Oka, Baylor College of Medicine) – Online
2:35 PM – 3:00 PM Clinical potential of MSC-EVs and translational challenges (Bernd Giebel, Essen University)
3:00 PM – 3:30 PM Coffee Break
Session Chairs: Beata Halassy (University of Zagreb, Croatia) and J. Michael Hatfield (Advanced Medicine Partners, USA)
3:30 PM – 3:55 PM Leveraging new CIMmultus QA HR for successful AAV polishing – optimization and scale up (Maja Leskovec, Sartorius BIA Separations)
3:55 PM – 4:20 PM Monoliths to bridge the gap between purity and yield in viral vectors downstream processing (Hana Jug, Sartorius BIA Separations)
4:20 PM – 4:45 PM Navigating successful characterization of AAV vectors: key steps to success (Alicja Fiedorowicz, Dark Horse Consulting Europe – Online